Thursday, May 16, 2024

Nursing-home referral service, A Place for Mom, is funded by nursing homes and has no information about their violations

Image from home page of A Place for Mom website
Kentucky Health News

The nation's largest nursing-home referral service, A Place for Mom, does not inform users about citations of facilities for neglect or other substandard care, The Washington Post reports.

A Place for Mom charges no fees to people seeking senior housing, but "is paid large fees by assisted-living facilities and does not independently assess their records," the Post reports. "More than a third of its most highly recommended facilities in 28 states were cited for neglect or substandard care in the past two years, many of them repeatedly."

Those 28 states put nursing-home inspection reports online, enabling the Post to easily research them. Kentucky is among the 22 states that do not put inspection reports online. Medicare's Nursing Home Compare website, which ranks facilities on a five-star systen, is based on those reports.

"A Place for Mom does not include these reports in its profiles of facilities, even in cases where poor care has led to death," the Post reports. 

Some places cite for substandard care have received a “Best of Senior Living” award from A Place for Mom for providing “exemplary care and support to aging loved ones.” The company says the awards are based on user reviews, "which are often anonymous," the Post reports.

"Current and former staff of some large chains told The Post that these reviews are often manipulated by the care providers; some claimed they were encouraged to obtain fake reviews from their own friends and relatives. . . . None of the sources suggested that A Place for Mom itself is involved in generating fake or manipulated reviews. But they say the site’s prominence creates incentives for facilities to push for favorable ratings."

15% fewer med-school grads applied for residencies in Kentucky this year; med-school association attributes that to abortion ban

Photo by Phallin Ooi, Creative Commons
By Sylvia Goodman
Kentucky Public Radio

The Association of American Medical Schools says 15 percent fewer U.S. medical-school graduates applied to Kentucky residency programs in the 2023-24 academic year, part of a trend related to states' strong anti-abortion laws enacted after the federal right to abortion was abolished. The decline was even greater in programs for obstetricians and gynecologists.
 
The study found that U.S. medical students were less likely to put in an application in states with abortion bans in place. The state's near-total abortion ban only allows exceptions if the mother is in imminent risk of death or permanent injury to a life-sustaining organ.

Dr. Atul Grover, executive director of the AAMS Research and Action Institute, found that 15% fewer U.S. medical students applied to residency programs in Kentucky during the last academic year compared to the 2022-23 school year. That’s 1,050 fewer applicants across specialties.

In OB-GYN programs, there was an even sharper 23% decline, Grover said. “We do see these trends across specialties, though,” he said. “People get a little jittery around the idea that the state government is going to come in and tell you what is not appropriate care for a patient when you know otherwise.”

Grover noted that medical students overall applied to fewer schools, meaning students got pickier in where they applied. That accounts for some of the decrease in applications across states, but the remaining deficit, he said, is cause for concern — particularly to states with abortion bans.

“Health-care shortages, across specialties, across a lot of states, are already being felt by patients,” Grover said. “If I think about Kentucky, Alabama, Mississippi, these are states that already have trouble attracting and recruiting, retaining physicians.”

Kentucky hospitals are already dealing with an “acute shortage” of health care workers, with nearly 13,000 job vacancies in hospitals at the end of 2022, says the Kentucky Hospital Association.

Grover said medical-residency application numbers are one of the fastest ways to measure where doctors are moving or interested in moving. Other metrics are harder and take longer to track. Residents have a tendency to stay in the state where they train.

Grover said lawmakers should understand the full implications of abortion bans, especially in a state that already suffers from several physician shortages, including in women and reproductive health fields. According to the U.S. Health Resources and Services Administration, more than half of Kentucky’s 120 counties didn’t have a single OB-GYN specialist in 2022-23.

Louisville pediatrician Dr. Michelle Elisburg said many doctors entering residency are in their mid-to-late 20s, and may be considering having children themselves. The bans may keep those women or their partners from considering moving to the state either.

“You wouldn't come if you're a young woman and know that if something happens to you, you might die because they aren't gonna let you get the health care you need,” Elisburg said. “That's where you are going to lose the doctors.”

Elisburg was part of the lobbying effort by Kentucky Physicians for Reproductive Freedom to end the state’s abortion bans this year.

She said the bans keep students from receiving all the training they need to provide abortion care or require them travel out of state to get it. “If there's such a ban, that restricts the kind of training that people are able to do,” she said. “They're not going to want to come to a state where they can't be completely trained in all the techniques in their field.”

Blair Wooten, who attended the University of Louisville medical school, said the state’s abortion ban was one of the reasons she decided to leave the state. She ended up going to a program in Ohio for the last year. She said abortion medical training “is paramount to me. It's something I want to be in my practice.”

Wooten is moving to a residency program in Indiana, which has its own abortion ban, but that program gives students the opportunity to receive abortion training in a Detroit-based program, which eased some of her fears — and clinics in Ohio are just a few hours drive away.

Wooten said she’s not sure if she’d consider setting up a practice in a state without abortion access. She said the inability to immediately provide the care she believes is necessary would be painful, but she also wants to provide services in health care deserts.

“Family planning is something I want to be a big part of my practice, so I usually say, ‘No’,” Wooten said. “But I'm also keenly aware that people need resources in every place, especially places that are maybe a little more hostile. And they need providers who care and can help them even with limited resources.”

Wednesday, May 15, 2024

As new Covid-19 variants become dominant and boosters are needed, vaccine misinformation continues; here are the facts

Photo from Getty Images via Kentucky Lantern
By Sarah Ladd
Kentucky Lantern

In the last month, new Covid-19 variants emerged as the dominant strain in the United States.

Covid-19 vaccines are still recommended for protection against the virus, and everyone who is 65 and over, or had medical conditions that make them more vulnerable, is advised to get a Covid-19 booster this spring.

The Cabinet for Health and Family Services says the KP.2 variant has already been confirmed in the state. Kentucky does not have any KP1.1 cases, cabinet spokesman Brice Mitchell said. These variants are in a group called FLiRT, after letters in the names of the individual mutations.

“These variants are not thought to cause more severe disease but do have some mutations in the spike protein that may make them more resistant to immunity conferred by vaccines and prior infections,” Mitchell said.

Kentucky has low levels of emergency-department visits and hospitalizations for Covid-19, but Mitchell said the state Department for Public Health “continues to recommend that all Kentuckians six months of age and older remain up-to-date with their Covid-19 vaccinations.”

A spokesperson for the Centers for Disease Control and Prevention told the Lantern that the CDC “continues to encourage Americans to get vaccinated, as the Covid-19 vaccination continues to be the best way to protect against serious illness.”

Despite that advice, not everyone is convinced. In the fourth year of Covid-19 — and about three and a half years since the vaccines arrived — misinformation about them persists, even among elected officials.

During the 2024 legislative session, vaccine misinformation — specifically around the Covid-19 shots — found its way onto the Kentucky Senate floor and into committee meetings. The Lantern consulted the CDC, the Food and Drug Administration and other sources in response to several vaccine claims made by lawmakers this year:
 
Claim: “The deaths and adverse events recorded to the Vaccine Adverse Events Report System that are submitted to this (Covid) vaccine total more than all other vaccines combined, since the CDC implemented the reporting system in 1990.”

Response: This claim has been debunked multiple times by multiple sources.

After Covid-19 vaccines became available, adverse reactions reported to the Vaccine Adverse Event Reporting System did increase, the CDC says, in part because so many people — more than 80% of Americans — received the shot. The 675 million doses of Covid-19 vaccine that have been administered in the U.S. are more than other types of vaccines. Also, under the emergency authorization for the Covid-19 vaccine, the FDA required health-care providers to report any adverse reaction in a patient even if it’s unclear the vaccine was the cause.

The Vaccine Adverse Event Reporting System is a voluntary early-warning system. Anyone may enter information about side effects or other adverse reactions after a vaccine; the reports are not verified, but scientists use the data to spot worrisome patterns that merit investigation.

"Anti-vaccination fringe groups have attempted to spin false stories using VAERS data, adding to misinformation about the safety of Covid-19 vaccinations," says the Johns Hopkins Bloomberg School of Public Health.

study published in the Journal of the American Medical Association in March found that the more likely a state was to vote Republican, the more likely its vaccine recipients or their clinicians reported adverse effects from Covid-19 vaccines. These results suggest that either the perception of vaccine effects or the motivation to report them was associated with political inclination.

Claim: “Covid-19 vaccines caused “unprecedented rise in sudden cardiac events, miscarriages and stillbirths, blood clots, myocarditis in youth, and sudden deaths among all ages.”

Response: Receiving the shot does not increase the risk of death from non-Covid causes. That conclusion is based on safety monitoring after more than 675 million doses of vaccine have been administered.

Covid-19 vaccination during pregnancy is safe and not linked to an increased risk of miscarriage or stillbirth, according to CDC safety monitoring and research. It has identified four rare but serious types of adverse events following Covid-19 vaccination. Two of them — thrombosis and Guillain-BarrĂ© Syndrome — were associated with vaccines that have been discontinued in the U.S. and are no longer available.

About 5 people per 1 million doses of vaccine have experienced anaphylaxis, a severe, potentially life-threatening allergic reaction that requires immediate emergency medical treatment. It can occur after any medication or vaccination.

Also, an increased risk of myocarditis – inflammation of the heart – is associated with the Pfizer and Moderna vaccines. Varying by age and sex, the rates of myocarditis after vaccination range from zero to 188 per 1 million doses. Research has found that the risk of myocarditis is higher following a Covid infection than after a Covid vaccine, according to the CDC.

CDC and FDA have detected no unusual or unexpected patterns indicating Covid-19 vaccines are causing or contributing to any other serious medical conditions.

Vaccination against Covid-19 reduces the risks of dying from Covid and suffering long Covid. The most common vaccine side effects are usually mild, such as soreness in the area where the shot was given.

Claim: “Pet vaccines are actually safer than people vaccines.”

Response: Animal and human vaccines undergo different approval processes. The U.S. Department of Agriculture’s Animal and Plant Health Inspection Service regulates veterinary vaccines and the Food and Drug Administration regulates human vaccines.

According to a 2014 paper in the National Library of Medicine, the two “differ markedly.” Vaccine effectiveness is more highly studied in human vaccines than in animal ones, that study found.

What the FDA says: The FDA “takes its responsibility for ensuring the safety, effectiveness and manufacturing quality of all vaccines approved or authorized for emergency use in the U.S. very seriously,” a spokesperson said.

All ingredients in new vaccines are looked at for safety and effectiveness. The “rigorous and extensive” approval process includes lab work, animal studies and human clinical trials.

“Highly trained FDA scientists and physicians thoroughly evaluate the information in a marketing application,” the FDA said, before ever approving shots for public distribution. Both pet and human vaccines are safe.

Monday, May 13, 2024

Food-as-medicine effort at UK gets a boost from new endowment

Alison Gustafson (UK photo by Sabrina Hounshell)
By Christopher Carney

One of the first two Gatton Foundation endowed professors at the University of Kentucky is Alison Gustafson, who directs the Food as Health Alliance. The endowment, from a $100 million gift by the late Bill Gatton, will provide funds to developing and expanding food-as-medicine programs across the state.

The money will help build capacity for health-care providers to get key services for diet-sensitive patients who are at risk of food insecurity. Gustafson is also developing and expanding community partnerships, offering approved food-as-medicine programs to those who qualify, and building a referral and network hub that will give patients a connection to services regardless of location. 

“Our team will be conducting expansion efforts for screening and referral, capacity building among community groups, outreach, UK Cooperative Extension training and research projects to better serve Kentuckians experiencing food insecurity,” Gustafson said. 

Gustafson is a professor in the Department of Dietetics and Human Nutrition in the Martin-Gatton College of Agriculture, Food and Environment and the College of Nursing. Under terms of the gift from the Bill Gatton Foundation, distinguished faculty get resources to continue meaningful research, extension and instructional programs related to advancing UK’s land-grant mission. 

The Food as Health Alliance was launched at UK in 2023 to boost health and well-being in the state through the combined application of agricultural, medical, and nutritional resources. Gustafson works to bring together clinical and community research to address the dual challenges of food insecurity and diet-related chronic diseases that many Kentuckians face.

Gustafson earned a doctoral degree in nutrition epidemiology from the University of North Carolina and a master's degree in public health from Boston University. As a master's student, she spent a year in Zimbabwe working with AIDS orphans. She has worked in local and state health departments, focusing on community health for disadvantaged populations. 

The other Gatton endowed chair, Tiffany Messer, will get support for student training and success, water-quality needs assessments, and low-cost water-quality treatment options. She is an associate professor of biosystems and agricultural engineering in the college.

Health-care industry is most at risk from cyberattack, study says

Health care is increasingly more at risk of cyberattacks than other industries, according to a recent study by Soax, a data-collection platform, reports Cara Smith of Inside Health Policy.

As cyberattacks against Change Healthcare and Ascension, a 19-state hospital system, "disrupted the health-care industry, lawmakers, doctors, payers and other stakeholders are scrambling to prevent future cyberbreaches to protect the health-care system," Smith reports.

"The health-care industry is the most vulnerable sector, topping the ranking with 809 data-violation cases in 2023. This is a staggering surge in incidents from the prior year, with cases totaling 343 in 2022 -- a 136% increase, the study found. Further data revealed that these cases affected 56 million victims."

For the study, Soax used data from the Identity Theft Resource Center, and it says "the health-care industry should be on high alert," Smith reports.

May is Bladder Cancer Awareness Month, and Kentucky ranks high; UK doctor explains it, and how to detect and manage it

Illustration by irkus Creative, iStock/Getty Images Plus
By Dr. Zin W. Myint
University of Kentucky

Kentucky has one of the highest rates of new cancers in the U.S., with bladder cancer in the top 10 list of new diagnoses. Understanding the signs, risk factors and preventive measures is important for early detection and management.

What are the symptoms and signs? The most common symptom of bladder cancer is the presence of painless blood in urine. If you notice blood in your urine, don't ignore it and go to your doctor right away. Other signs to look out for are more frequent urination and an increased urge to urinate, especially accompanied by pain or discomfort. Persistent pain in the lower back or pelvic region that only gets worse over time is also a symptom.

What can increase the risk of developing bladder cancer?
  • Smoking is the biggest risk factor. Tobacco smoke contains many harmful chemicals that can damage the bladder lining, increasing the risk of developing cancer.
  • Exposure to certain industrial chemicals such as paint, dye, metal processing and petroleum products.
  • Family history and genetics. If your family has a history of bladder cancer, you should be tested if you notice any of the symptoms above.
  • Some chemotherapy drugs and medications are linked to bladder cancer increased because they can irritate the bladder.
  • Environmental factors, including drinking water contaminated with arsenic.
  • Chronic urinary tract infections may contribute to bladder cancer development as chronic inflammation causes damage to the protective layer of cells lining the bladder.
  • A personal history of bladder cancer is also a risk factor, due to its high recurrence rate.
  • Other risk factors include chronic indwelling urinary catheter or history of radiation to the pelvic area.
Is there a screening for bladder cancer? We do not screen for bladder cancer in the general population because current studies do not show sufficient benefit.

How can you reduce risks? Reducing the risk of bladder cancer stars with adopting healthy lifestyle choices and minimizing exposure to known risk factors:
  • Quitting smoking is one of the most effective ways to reduce the risk of bladder cancer, creating a healthy bladder lining. We highly advocate for smoking cessation, and individuals who smoke should be actively encouraged to pursue cessation treatments, which may include medication and counseling. It is advisable to engage in discussions with your healthcare provider to explore effective methods for quitting smoking and receive personalized support tailored to your needs.
  • Minimize or avoid chemical exposure and take safety precautions when working with chemicals that are known to be harmful. For instance, remember to wear gloves while using potent cleaning agents at home as numerous chemicals can permeate the skin. If you’re employed in a refinery setting, prioritize the use of protective gear. Similarly, if you’re a painter, ensure to work within well-ventilated areas to minimize exposure to potentially harmful substances.
  • Stay hydrated. Drinking plenty of water throughout the day is vital for maintaining bladder health, reducing the risk of urinary tract infections, and facilitating the swift elimination of toxins from your system.
Zin W. Myint, M.D., is a medical oncologist at UK Markey Cancer Center.

Sunday, May 12, 2024

Falling immunization rates pose threats to Kentucky and the rest of nation; immunization climate remains 'turbulent,' observer says

Foundation for a Healthy Kentucky photo
By Melissa Patrick
Kentucky Health News

The immunization crisis in Kentucky is not just a Kentucky issue, but is happening nationwide.

"It's not going to take long before we see the effects of falling rates of immunizations. We're seeing some decrease across the board, again, from coast to coast, border to border," said Dr. Christopher Bolling, who represented the Kentucky Chapter of the American Academy of Pediatrics on a May 8 webinar hosted by the Foundation for a Healthy Kentucky titled “Tackling the Immunization Crisis.”

Bolling said many people have a "false view" that nothing will happen because of these falling immunization rates because it's been so long since we've seen the illnesses that they protect against.

As a recent example, on May 7, the Lexington-Fayette County Health Department reported another cases of pertussis, or whooping cough. It was the city's third case since late April. Since April 1, cases have also been confirmed in Boyd, Jessamine, Logan, Pulaski and Warren counties.

Brice Mitchell, spokesperson for the state Cabinet for Health and Family Services, told Kentucky Health News that there were 84 confirmed cases of pertussis in Kentucky in 2023, and 32 confirmed so far in 2024 -- about the same rate, but dependent on confirmations that may be delayed.

Looking forward during the webinar, Bolling said it's important to not let the controversies surrounding the Covid-19 vaccine influence people's decisions to get vaccinated against other diseases.

"We really do not want to see it start affecting other vaccines as well," he said. 

Looking at Kentucky's vaccination rates, he said that with the exception of young children's diphtheria, tetanus and pertussis vaccines, Kentucky's vaccination rates are lower than the national averages. 

In particular, Bolling pointed to Kentucky's low measles-mumps-rubella vaccination rate. He said Kentucky's rate is 90.1%, the national rate is 93.1% and the level to achieve herd immunity is 95%. 

"So we are susceptible," he said. Herd immunity is the level needed to protect people who can't or won't be vaccinated for various reasons.

Bolling offered suggestions for health-care providers and others for how to talk to people about immunizations and fight misinformation. He said it's important to always remember that behavior changes must be self-motivated.

"The choices they make are going to be based on their own values, their own standards, and their own understanding," he said. "So you really want to evoke within them things that are going to help them make good decisions." 

Kelly Taulbee, director of communications and development at Kentucky Voices for Health, called the current climate around immunizations a "turbulent space." 

"Something to keep in context is you have entire families that don't talk to each other anymore, friends that have lost connection simply because of the positions they took during the pandemic on immunizations," she said. 

Taulbee stressed that the importance of keeping an eye on policies that would hurt the state's immunization rates, pointing to eight bills that were filed in the 2024 legislative session that did not pass. 

Jessy Sanders, health communicator program manager for the Kentucky Rural Health Association's Immunize Kentucky Coalition, announced their upcoming events. Symposiums will be held in Hazard May 17, Somerset Aug. 8 and Paducah Aug. 23, and the 2024 Immunization Summit will be held Oct. 9. 

AMA president-elect, from Louisville, lays out his ideas for getting more physicians in rural areas, reforming prior authorization

By Melissa Patrick
Kentucky Health News

With about 46 million people in the U.S. living in rural areas and new research showing they are more likely to die early from the five leading causes of death than their urban counterparts, the American Medical Association is sounding the alarm. 

AMA President-elect Bruce Scott (AMA photo)
"Rural health is America's health," Dr. Bruce Scott of Louisville, AMA president-elect, told reporters in a May 9 press conference in conjunction with the National Rural Health Association annual conference in New Orleans. "We need policymakers to understand that the American Medical Association is deeply concerned about the ever-widening health disparities between urban and rural communities. disparities that are at the root of why rural Americans suffered disproportionately high rates of heart disease, cancer, stroke, respiratory illness, diabetes, and unintentional injuries." 

Scott, who is board-certified in both otolaryngology and facial plastic surgery, served as the Kentucky Medical Association's president in 2018-19. He will become AMA president in June. 

Scott pointed to several environmental, economic and social factors factors that put people who live in rural communities at a higher risk of death from these often preventable conditions. But the AMA's focus, he said, is on the health-care worker and the physician shortage and how this affects rural people's health. 

He added that these shortages are hitting rural areas the largest and are "creating health-care trends that are simply unacceptable. We need to reverse these trends for all individuals to live a long, healthy and active life."

Scott said rural areas have about 30 physician specialists for every 100,000 residents, compared to 236 per 100,000 in urban communities, and he noted that more than 130 rural hospitals closed from 2010 to 2021, with many more on the verge of closing today. 

Also, he said that in 2023, 65% of rural communities had insufficient access to primary-care physicians, including pediatricians. And, he said there are not enough residency spots to train doctors in rural areas. 

"History has shown us that residents, 80% of the time, tend to wind up practicing within 80 miles of where they've done the residency," Scott said. "So residency location becomes very important. In addition, medical schools are receiving fewer and fewer applicants from individuals from rural areas."

Call for Medicare reform

Scott said the AMA is working to build a stronger physician workforce, which he said starts with supporting physicians who are already in practice, to keep them practicing.

"AMA is focused on fixing the systemic issues of our health-care system that are known to be driving physician burnout, and contributing to early retirement and physicians leaving practice altogether," he said. "Highest among these problems are the broken Medicare physician payment system and the administrative burdens." 

The problem, said Scott, is that Medicare payments to doctors are not keeping up with inflation. He said that when adjusted for inflation, the payment rate to physicians has dropped 29% since 2001, and private payers and other insurers have linked their payments to the Medicare structure. 

"We need a system that is sustainable, predictable, and provides at least an annual inflation update that encourages patients choice rather than consolidation," he said. "We need Congress to act." 

Administrative burdens

Scott said physicians spend two hours on administrative work for every one hour with patients, contributing to burnout and hindering patient care. 

A key contributor to this is "prior authorization," which requires a physician to get approval from a third-party payer for care that the physician and patient have agreed on before it can be implemented.  

"On average, physicians complete 45 prior authorizations per week and it's even worse in primary care," Scott said. "The prior authorization process is overused, overly burdensome and wastes physicians' time. But I'm even more concerned about the fact that prior authorization hurts patients." 

He added, "We need Congress and payers and the administration to respond, because the result is that physicians are getting burned out and they're leaving practice, not because they don't want to practice medical care anymore, but because the system is making it more and more difficult for them to care for their patients." 

During the 2024 legislative session, Rep. Kim Moser, R-Taylor Mill, again filed a bill to address the prior authorization issue in Kentucky, but health insurers blocked it. It would have exempted from the process health-care providers who have had 90% or more of their claims approved. 

Scott said the AMA is "fighting for legislation fixes" to increase incentives for physicians to work in rural areas, to expand the number of residency spots, particularly in primary care and in rural areas, to make the pandemic's telehealth flexibilities permanent, and to allow qualified international medical graduates to keep practicing in America. 

Asked about the role of advanced-practice registered nurses and physician assistants to help increase access to care in rural areas, Scott said that "there is absolutely" a role for these "physician extenders" in a physician-led team model. 

"The AMA believes strongly in the concept of a physician-led medical team, where every component of the team is working to the highest level of their knowledge base and their experience," he said. "Now, we're not in favor of independent practice for nurse practitioners or PAs. We think that patients, no matter what ZIP code they happen to live in, deserve care by a physician." 

Saturday, May 11, 2024

Most Kentucky hospitals in national patient-safety ratings got 'C' grades again; state is 35th in share of hospitals with 'A' ratings

By Melissa Patrick
Kentucky Health News

Most of the Kentucky hospitals graded on a nonprofit group's twice-a-year report card for patient safety again got a C in the latest report. 

The Leapfrog Group, based in Washington, D.C., rates nearly 3,000 general acute-care hospitals based on how well they protect patients. Most of Kentucky's 126 hospitals are relatively small, so they are not rated by Leapfrog; it rated 62 Kentucky hospitals.

The group does not grade small hospitals with "critical access" status because they don't have to report quality measures to the federal government; nor does it grade specialty hospitals, government hospitals, or hospitals that don't have enough publicly reported data.

Leapfrog gave 'A' ratings to 10 Kentucky hospitals; Kentucky's percentage of A grades, 16.4%, ranked it 35th among states. That was up two slots from the last report, when it ranked 37th. Leapfrog gave Bs to 19 Kentucky hospitals, Cs to 27 and Ds to 5.  

The grades are based on more than 30 measures that indicate how well hospitals protect patients from preventable errors, injuries, accidents and infections. 

The spring 2024 report showed 92% of U.S. hospitals have seen improvements in at least one of three infections associated with hospitals. Methicillin-resistant Staphylococcus aureus (MRSA) decreased by 30%, central line-associated bloodstream infections decreased by 34% and catheter-associated urinary tract infections decreased by 30%. This good news comes after a six-year high for those infections was reported in the fall 2022 report. 

"While today’s results are promising, patient safety remains a crisis-level hazard in health care. Some hospitals are much better than others at protecting patients from harm, and that’s why we make the Hospital Safety Grade available to the public and why we encourage all hospitals to focus more attention on safety,” Leah Binder, president and CEO of The Leapfrog Group, said in a news release. 

She added, "According to a summary of peer-reviewed research published in British Medical Journal, an estimated 250,000 people a year die of preventable errors and infections in hospitals, which makes patient safety problems the third leading cause of death in the United States." 

The spring 2024 report also showed some improvements on patient experience measures compared to fall 2023. The release notes that these measures worsened during the pandemic and have still not returned to pre-pandemic levels. These measures look at things that have a direct impact on patient safety outcomes, including nurse communication, doctor communication, hospital staff responsiveness, communication about medicine and discharge information. 

"Patient experience is very difficult to influence without delivering better care," Binder said, "so these findings are encouraging."

The Leapfrog site offers details on the measures for each hospital under the heading Infections. It also provides detailed information under headings titled Problems with Surgery, Practices to Prevent Errors, Safety Problems, and Doctors, Nurses and Hospital Staff. The information is provided in an easy-to-read, color-coded scale that indicates how the hospital is performing.

The report uses data from the Centers for Medicare and Medicaid Services, Leapfrog's own survey and other supplemental data sources. Leapfrog says hospitals are only graded if they have submitted adequate data for evaluation.

Top Scores

Hospitals getting As were Baptist Health La Grange, Baptist Health Lexington, Deaconess Henderson Hospital, Georgetown Community Hospital, Meadowview Regional Medical Center in Maysville, the Medical Center at Bowling Green, Saint Joseph-London, St. Elizabeth Healthcare-Edgewood, T.J. Samson Community Hospital in Glasgow, and TriStar Greenview Regional Hospital in Bowling Green.  

Screenshot of page for Georgetown Community Hospital
Georgetown Community Hospital received an A after getting six consecutive Cs.

Baptist Health Lexington has received an A grade for 13 consecutive grading periods. Deaconess Henderson moved up from a B grade in the fall 2023 report. The rest in this top group also received As in the fall. 

Shifts up and down

Four Kentucky hospitals moved down to a B after getting an A on the last report, including Norton Audubon Hospital, Norton Brownsboro Hospital, Norton Hospital and Norton Women's & Children, all in Louisville. 

Five Kentucky hospitals moved up to a B after getting a C on the last report, including Baptist Health Deaconess Madisonville, Baptist Health Richmond, Harrison Memorial Hospital in Cynthiana, Middlesboro ARH Hospital and the University of Kentucky Albert B. Chandler Hospital

Other hospitals with B grades are Baptist Health Louisville, Baptist Health Paducah, Clark Regional Medical Center in Winchester, Owensboro Health Muhlenberg Community Hospital in Greenville, Saint Joseph East in Lexington, St. Elizabeth Healthcare-Fort Thomas, St. Elizabeth Healthcare-Florence, U of L Health Shelbyville Hospital, UK HealthCare Good Samaritan Hospital and Blanchfield Army Community Hospital in Fort Campbell. 

Five Kentucky hospitals moved up from a D to a C: Hazard ARH Regional Medical Center, Jackson Purchase Medical Center in Mayfield, Jewish Hospital in Lexington, Kentucky River Medical Center in Jackson and UofL-Sts. Mary and Elizabeth Hospital

Three hospitals moved down from a B to a C: Kings Daughters Medical Center in Ashland, Monroe County Medical Center in Tompkinsville and Whitesburg ARH Hospital

The remaining 19 hospitals with a C all got Cs on the last report card too. 

Taylor Regional Hospital in Campbellsville moved down from a C to a D and Jennie Stuart Health in Hopkinsville moved up to a D after being the only hospital in the fall 2023 report to get an F. 

Other hospitals with D grades are Highlands ARH Regional Medical Center in Prestonsburg, Murray-Calloway County Hospital and Pikeville Medical Center

No Kentucky hospitals got an F on this report. 

Click here for a list of frequently asked questions about the survey. Click here to see if your hospital was graded. 

Online vision retailer Warby Parker will pay Ky. civil penalty for letting 69 Kentuckians to take its online vision test, illegal in Ky.

Image on Warby Parker's "Get a Prescription" page
Kentucky Health News

Warby Parker, an online retailer of prescription glasses, contact lenses and sunglasses, has agreed to pay at least $55,200 to the Commonwealth of Kentucky for allowing 69 Kentuckians to take its online vision test, contrary to state law, Attorney General Russell Coleman's office said in a news release Friday.

Coleman's office alleged that from July to October 2021, 69 Kentuckians were improperly given Warby Parker’s online test. "When the attorney general’s Office of Consumer Protection alerted Warby Parker of the problem, the company cooperated with the investigation and took the test offline," the release said. "Following a voluntary settlement process, Warby Parker will be penalized $138,000. If there are no further violations for five years, the amount will be reduced to $55,200."

The "Get a Prescription" page on Warby Parker's website says the online vision test is available to people who "reside in an eligible state, due to state-level regulations," and disqualifies residents of Alaska, Connecticut, the District of Columbia, Georgia, Idaho, Kentucky, New Mexico, South Carolina, South Dakota, Washington and West Virginia, using their two-letter postal abbreviations.

Kentucky consumers may complain about a business operating in the state to Coleman’s office at https://www.ag.ky.gov/Resources/Consumer-Resources/Consumers/Pages/Consumer-Complaints.aspx.

Friday, May 10, 2024

17 Ky. schools have free online mental health wellness course

Kentucky Health News map; for a larger version, click on it
More than 1,500 students in 17 Kentucky schools recently gained access to a free digital course on mental wellness, provided by the Medicaid program of Anthem Inc., one of the health insurers that manages the federal-state health program in Kentucky.

"The announcement comes during Mental Health Awareness month and as more adolescents, especially girls, report depressive symptoms," notes Sarah Ladd of the Kentucky Lantern.

The 17 schools in the program are Clay County Middle School, Daviess County High School, Estill County High School, Grant County Middle School, Graves County High School, Grayson County Middle School, Hazard Middle School, Henderson County High School, Bazzell Middle School in Allen County, Jenkins Independent School in Letcher County, Lewis County Central Elementary School, Marion County High School, Murray Middle School in Calloway County, Ohio County Middle School, Owensboro Middle School, Russell High School in Greenup County and Webster County High School.

The program has been launched in these schools and will continue into the 2024-25 academic school year, according to Quin Welch, media contact for Anthem Medicaid.

Understanding Mental Wellness” is a course for students in grades 8, 9 and 10. It has six 15-minute lessons, according to Blackbaud, the digital-services firm that designed the course. 

Anthem says the course exposes students “to the experiences of others in order to develop awareness and empathy, reduce stigma, and provide facts on the prevalence and symptoms of mental health conditions.”

Students then “explore their own mental health, identify challenges they may face, and develop concrete strategies for managing those challenges while increasing their awareness of resources and empowering them with the knowledge, skills, and language necessary to identify and support a peer in need or at risk.”

Ladd reports, "Online previews of the course show a tour of mental health through the program, starting with a lesson on what mental health is and ending with the chance to create a personal wellness plan.

"Since the onset of Covid-19, mental health has worsened. In 2021, the Centers for Disease Control and Prevention found that sadness and hopelessness had increased from pre-pandemic levels, especially for teen girls. In 2017, 41% of female high school students and 21% of male high school students felt sad or hopeless. By 2021, those statistics were at 57% and 29%, respectively."

“Young people need resources and education from trusted sources to protect their mental health,” said Leon Lamoreaux, market president for Anthem Medicaid. He said the program “will help us reach students from all over the Commonwealth and equip them with tools and strategies that will make a positive difference in their lives for years to come.”

Tom Davidson, the CEO of Everfi, said the goal of the program is to help “those who are impacted by mental-health challenges, those who want to build and maintain positive mental health and those who have the opportunity to positively impact the mental health of a friend or peer.”

Thursday, May 9, 2024

Parkinson's disease: Its symptoms, causes and management

Photo illustration by Pornpak Khunatorn, iStock/Getty Images Plus
By Dr. Zain Guduru
University of Kentucky

Parkinson's disease is a progressive neurological disorder that affects movement. Named after Dr. James Parkinson, who first described it in 1817, this condition currently affects millions of people worldwide. While there is no cure for Parkinson's disease, understanding its symptoms, causes and management strategies can significantly improve the quality of life for those living with the condition.

What is Parkinson's disease? PD primarily affects the brain's nerve cells responsible for producing dopamine, a neurotransmitter involved in movement regulation. As these cells degenerate or become impaired, dopamine levels drop, leading to the characteristic symptoms of PD.

Symptoms of Parkinson's disease:
  • Tremors: Involuntary shaking, usually starting in the hands or fingers.
  • Bradykinesia: Slowed movement and difficulty initiating movement.
  • Muscle rigidity: Stiffness in the limbs or trunk, causing difficulty with movement.
  • Postural instability: Impaired balance and coordination, leading to falls.
  • Non-motor symptoms: These can include depression, anxiety, cognitive changes and sleep disturbances.
Causes of Parkinson's disease: The exact cause of PD remains unknown, but it's believed to involve a combination of genetic and environmental factors. Some potential factors that may contribute to the development of PD include:
  • Genetic mutations: Certain genetic mutations have been linked to an increased risk of Parkinson's disease.
  • Environmental factors: Exposure to toxins like pesticides, herbicides and heavy metals may increase the risk.
  • Age: The risk of Parkinson's disease increases with age, typically affecting individuals over the age of 60.
  • Brain changes: Abnormal protein deposits in the brain, such as alpha-synuclein, are associated with Parkinson's disease.
Managing Parkinson's disease: While there is no cure for PD, several treatment options can help manage its symptoms and improve quality of life:
  • Medications: Dopamine replacement medications, such as levodopa, can help alleviate motor symptoms.
  • Physical therapy: Exercise programs designed to improve flexibility, balance, and mobility can be beneficial.
  • Speech therapy: Speech therapists can help with communication difficulties often associated with Parkinson's disease.
  • Deep brain stimulation: In advanced cases, DBS surgery may be an option to help control motor symptoms.
  • Lifestyle modifications: Eating a balanced diet, staying physically active, and managing stress can all contribute to better symptom management.
Parkinson's disease is a complex condition that requires a multidisciplinary approach to management. While there is no cure, early diagnosis and appropriate treatment can significantly improve the quality of life for individuals living with PD. By raising awareness, supporting research, and implementing effective management strategies, we can work towards a better understanding and treatment of Parkinson's disease.

Zain Guduru, M.D., is a neurologist with the Kentucky Neuroscience Institute and assistant professor in the University of Kentucky College of Medicine.

Tuesday, May 7, 2024

Stomach cancer: How to recognize the signs and reduce your risk

Illustration by peterschreiber.media via iStock/Getty Images Plus
By Dr. Joseph Kim
University of Kentucky

While stomach cancer was in the headlines not long ago with the sudden death of musician Toby Keith, the diagnosis is relatively rare. Stomach cancer now accounts for 1.4% of new cancer cases in the U.S., down from nearly 10% from 30 years ago.

With an average age at diagnosis of 68, stomach cancer is more common among older individuals. But it can happen to anyone, so it’s important to understand its symptoms, risk factors and steps you can take to lower your risk.

What are the signs and symptoms of stomach cancer? Early stage stomach cancer often has no symptoms. As the cancer progresses, patients may experience abdominal pain or discomfort, feeling bloated or full after eating small amounts, nausea or vomiting, unexplained weight loss, blood in the stool and difficulty swallowing.

What causes stomach cancer? There are not always clear risk factors for developing stomach cancer, but some factors tend to be associated with the onset of the disease. These include:
  • Heavy consumption of smoked, salted and processed meats
  • A diet low in fruits, vegetables and fiber rich foods
  • Smoking tobacco
  • Being overweight or obese
Other risk factors include gastroesophageal reflux disease (GERD), a family history of stomach cancer, Epstein-Barr virus and H. pylori bacterial infection.

What can I do to reduce my risk? While there is no guaranteed way to prevent stomach cancer, you can lower your risk by:
  • Eating a balanced diet with plenty of fruits, vegetables and whole grains. Limit processed meats and smoked or salty foods.
  • Maintaining a healthy weight through diet and exercise
  • Quitting smoking and limiting alcohol consumption
Can I get screened for stomach cancer? Routine screening isn't currently recommended for everyone. But if you have certain risk factors, like H. pylori infection or a family history of stomach cancer, talk to your doctor about screening options like upper endoscopy or blood tests.

While treatments have progressed in recent years, the five-year relative survival rate for stomach cancer is 35.7%. Early detection can make all the difference for better treatment outcomes, so don't hesitate to reach out to your health care provider if you experience any symptoms or have risk factors that warrant screening.

Joseph Kim, M.D., is a surgeon at the UK Markey Cancer Center.

Sunday, May 5, 2024

Kentucky Center for Smoke-Free Policy honors communities, groups and individuals who help create smoke-free communities

The Kentucky Center for Smoke-Free Policy at the University of Kentucky and the Kentucky Department for Public Health’s Tobacco Prevention & Cessation Program honored communities, groups and individuals from across the state who are leading the way to enact smoke- and tobacco-free policies at the 2024 Kentucky Tobacco Control Conference held April 23-24 in Lexington. 

“While tobacco use has decreased across the general population, disparities persist by geographic location, socioeconomic status, race, ethnicity, sexual orientation, gender identity, disability status, and mental health status,” Amanda Bucher, director of tobacco policy research and outreach in the College of Nursing at UK, said in a news release. “This is in part due to the tobacco industry’s targeted marketing of these populations. Our vision for a tobacco-free Kentucky must promote health equity and eliminate these disparities.”

Sydney Shaffer, the 2024 Smoke-free Youth
Advocate of the Year, poses with Lexington
Mayor Linda Gorton. (Photo by Tim Webb)
Sydney Shaffer, a high-school student from Scott County, received the Smoke-free Youth Advocate Award for excellence in promoting smoke-free policy and education about secondhand smoke. Shaffer has advocated for lung-health policies and youth-vaping prevention since losing her grandfather to lung cancer. She has spoken to policymakers about the importance of tobacco control policies at the local, state and national levels.

The Northern Kentucky towns of Corinth and Highland Heights received the Everette Varney Smoke-free Indoor Air Excellence Award for their "exceptional leadership" and collaborative efforts in promoting the health of their citizens by enacting comprehensive smoke-free workplace ordinances.

Dr. Timothy W. Mullett, medical director of UK's Markey Cancer Center Network, received the Lee T. Todd Jr., Smoke-free Hero Award for his courage, leadership, perseverance, and continuous commitment to smoke- and tobacco-free environments in the face of adversity.

Centre College received the Tobacco Free Campus Award for its exceptional leadership and collaborative efforts in promoting healthy campus environments by implementing a tobacco-free campus last year.

Jelaine Harlow, health-education coordinator for the Lake Cumberland District Health Department, received the Ellen J. Hahn Lifetime Achievement in Tobacco Control Award for an exceptional life devoted to leadership in advocacy and public service contributions in tobacco control.

Jessica L. Burris, UK Department of Psychology and Markey Cancer Center received the Timothy W. Mullett M.D. Lung Cancer Prevention Award for her leadership, devotion, and passion toward preventing lung cancer through policy change in tobacco control.

Dr. Michael Gieske, diredctor of lung-cancer screening at St. Elizabeth Healthcare in Northern Kentucky, received the David B. Stevens M.D. Smoke-free Advocate of the Year Award for excellence in promoting secondhand smoke education and smoke-free policy.

The event was also sponsored by UK Healthcare, the Kentucky Health Collaborative, the Kentucky Asthma Management ProgramAetna Better Health of Kentucky, the Kentucky Office of Community Health WorkersAppalachian Regional Healthcare, the Kentucky COPD ProgramCHI Saint Joseph Health and Kentucky Voices for Health, a coalition of health-advocacy organizations.

Friday, May 3, 2024

2% fewer Ky. children were on Medicaid a year after pandemic re-enrollment began; total enrollment, including adults, dropped 9.5%

Top half of Georgetown University table, adapted by Ketucky Health News; to enlarge, click on it.
By Melissa Patrick
Kentucky Health News

Medicaid enrollment of Kentucky's children fell 1.6 percent since the continuous-coverage protections of the pandemic were lifted last year. That was one of the smallest declines in the nation.

Coverage of U.S. children fell 10% in the "unwinding" process, says the report from the Georgetown University Center for Children and Families, based on data from the Centers for Medicare and Medicaid Services.

Kentucky hasn't started the re-enrollment process for children yet because, unlike most states, it worked with the federal government to delay the restart of renewals for children until this September. So did North Carolina.

"The story of Georgetown's report is an incredible good news story that speaks to how well Kentucky did things for kids," said Priscilla Easterling, outreach coordinator for Kentucky Voices for Health, a coalition of health-care advocacy groups.

Nationwide, 4.16 million children were dropped from from Medicaid and the Children's Health Insurance Program, and most would likely still be eligible, says the report. The numbers do not reflect individual children, but the change in total enrollment, which fluctuates from month to month for various reasons.

In Kentucky, 10,477 fewer children were covered than the 648,865 who were enrolled in either Medicaid or KCHIP before the unwinding -- the gradual resumption of annual Medicaid coverage renewals. Renewals in Kentucky began in April 2023.

Overall, Kentucky's Medicaid rolls have declined 9.5 percent in the last year. The number enrolled in April was 1,561,400. County-by-county figures are available from the Cabinet for Health and Family Services.

Cabinet spokesperson Brice Mitchell told Kentucky Health News in an email that Kentucky was the first state to request and get approval to automatically grant children 12 months of continuous coverage, without needing to go through a renewal during the unwinding. 

"The state sought this flexibility to ensure our children kept access to the coverage they need and deserve," Mitchell said. 

The only way a child may be disenrolled during the 12-month continuous coverage period is if the child turns 19, a parent or guardian requests disenrollment, or if the child moves out of state, Mitchell said. 

Easterling said it is expected that the children's renewal period that begins in September will go smoothly since the state will have already processed the adult renewals. 

She also noted that it would be great if the state took advantage of an existing program that would allow continuous coverage for children up to age 3 as some other states have done.  

"We know that kids losing coverage and being uninsured negatively impacts their health and their family's finances, with the risk of big medical bills . . . that a family can't afford to pay," Easterling said.

Bird flu is bad for livestock; it's not a dire threat to most of us - yet

Getty Images
By Amy Maxmen
KFF Health News

Headlines are flying after the U.S. Department of Agriculture confirmed that the H5N1 bird flu virus has infected dairy cows around the country. Tests have detected the virus among cattle in nine states, mainly in Texas and New Mexico, and most recently in Colorado, said Nirav Shah, principal deputy director at the Centers for Disease Control and Prevention, at a May 1 event held by the Council on Foreign Relations.

A menagerie of other animals have been infected by H5N1, and at least one person in Texas. But what scientists fear most is if the virus were to spread efficiently from person to person. That hasn’t happened and might not. Shah said the CDC considers the H5N1 outbreak “a low risk to the general public at this time.”

Viruses evolve and outbreaks can shift quickly. “As with any major outbreak, this is moving at the speed of a bullet train,” Shah said. “What we’ll be talking about is a snapshot of that fast-moving train.” What he means is that what’s known about the H5N1 bird flu today will undoubtedly change.

With that in mind, KFF Health News explains what you need to know now.

Who gets the bird flu? Mainly birds. Over the past few years, however, the H5N1 bird flu virus has increasingly jumped from birds into mammals around the world. The growing list of more than 50 species includes seals, goats, skunks, cats, and wild bush dogs at a zoo in the United Kingdom. At least 24,000 sea lions died in outbreaks of H5N1 bird flu in South America last year.

What makes the current outbreak in cattle unusual is that it’s spreading rapidly from cow to cow, whereas the other cases — except for the sea-lion infections — appear limited. Researchers know this because genetic sequences of the H5N1 viruses drawn from cattle this year were nearly identical to one another.

The cattle outbreak is also concerning because the country has been caught off guard. Researchers examining the virus’s genomes suggest it originally spilled over from birds into cows late last year in Texas, and has since spread among many more cows than have been tested. “Our analyses show this has been circulating in cows for four months or so, under our noses,” said Michael Worobey, an evolutionary biologist at the University of Arizona in Tucson.

Is this the start of the next pandemic? Not yet. But it’s a thought worth considering because a bird flu pandemic would be a nightmare. More than half of people infected by older strains of H5N1 bird flu viruses from 2003 to 2016 died. Even if death rates turn out to be less severe for the H5N1 strain currently circulating in cattle, repercussions could involve loads of sick people and hospitals too overwhelmed to handle other medical emergencies.

Although at least one person has been infected with H5N1 this year, the virus can’t lead to a pandemic in its current state. To achieve that horrible status, a pathogen needs to sicken many people on multiple continents. And to do that, the H5N1 virus would need to infect a ton of people. That won’t happen through occasional spillovers of the virus from farm animals into people. Rather, the virus must acquire mutations for it to spread from person to person, like the seasonal flu, as a respiratory infection transmitted largely through the air as people cough, sneeze, and breathe. As we learned in the depths of covid-19, airborne viruses are hard to stop.

That hasn’t happened yet. However, H5N1 viruses now have plenty of chances to evolve as they replicate within thousands of cows. Like all viruses, they mutate as they replicate, and mutations that improve the virus’s survival are passed to the next generation. And because cows are mammals, the viruses could be getting better at thriving within cells that are closer to ours than birds’.

The evolution of a pandemic-ready bird flu virus could be aided by a sort of superpower possessed by many viruses. Namely, they sometimes swap their genes with other strains in a process called reassortment. In a study published in 2009, Worobey and other researchers traced the origin of the H1N1 “swine flu” pandemic to events in which different viruses causing the swine flu, bird flu, and human flu mixed and matched their genes within pigs that they were simultaneously infecting. Pigs need not be involved this time around, Worobey warned.

Will a pandemic start if a person drinks virus-contaminated milk? Not yet. Cow’s milk, as well as powdered milk and infant formula, sold in stores is considered safe because the law requires all milk sold commercially to be pasteurized. That process of heating milk at high temperatures kills bacteria, viruses, and other teeny organisms. Tests have identified fragments of H5N1 viruses in milk from grocery stores but confirm that the virus bits are dead and, therefore, harmless.

Unpasteurized “raw” milk, however, has been shown to contain living H5N1 viruses, which is why the FDA and other health authorities strongly advise people not to drink it. Doing so could cause a person to become seriously ill or worse. But even then, a pandemic is unlikely to be sparked because the virus — in its current form — does not spread efficiently from person to person, as the seasonal flu does.

What should be done? A lot! Because of a lack of surveillance, the U.S. Department of Agriculture and other agencies have allowed the H5N1 bird flu to spread under the radar in cattle. To get a handle on the situation, the USDA recently ordered all lactating dairy cattle to be tested before farmers move them to other states, and the outcomes of the tests to be reported.

But just as restricting covid tests to international travelers in early 2020 allowed the coronavirus to spread undetected, testing only cows that move across state lines would miss plenty of cases.

Such limited testing won’t reveal how the virus is spreading among cattle — information desperately needed so farmers can stop it. A leading hypothesis is that viruses are being transferred from one cow to the next through the machines used to milk them.

To boost testing, Fred Gingrich, executive director of a nonprofit organization for farm veterinarians, the American Association of Bovine Practitioners, said the government should offer funds to cattle farmers who report cases so that they have an incentive to test. Barring that, he said, reporting just adds reputational damage atop financial loss.

“Outbreaks have a significant economic impact,” Gingrich said. “Farmers lose about 20% of their milk production in an outbreak because animals quit eating, produce less milk, and some of that milk is abnormal and then can’t be sold.”

The government has made H5N1 tests free for farmers, Gingrich added, but hasn’t budgeted money for veterinarians who must sample the cows, transport samples, and file paperwork. “Tests are the least expensive part,” he said.

If testing on farms remains elusive, evolutionary virologists can still learn a lot by analyzing genomic sequences from H5N1 viruses sampled from cattle. The differences between sequences tell a story about where and when the current outbreak began, the path it travels, and whether the viruses are acquiring mutations that pose a threat to people. The research has been hampered by the USDA’s slow and incomplete posting of genetic data, Worobey said.

The government should also help poultry farmers prevent H5N1 outbreaks since those kill many birds and pose a constant threat of spillover, said Maurice Pitesky, an avian disease specialist at the University of California-Davis.

Waterfowl like ducks and geese are the usual sources of outbreaks on poultry farms, and researchers can detect their proximity using remote sensing and other technologies. By zeroing in on zones of potential spillover, farmers can target their attention. That can mean routine surveillance to detect early signs of infections in poultry, using water cannons to shoo away migrating flocks, relocating farm animals, or temporarily ushering them into barns. “We should be spending on prevention,” Pitesky said.

OK, it’s not a pandemic, but what could happen to people who get this year’s H5N1 bird flu? No one really knows. Only one person in Texas has been diagnosed with the disease this year, in April. This person worked closely with dairy cows, and had a mild case with an eye infection. The CDC found out about them because of its surveillance process.

Clinics are supposed to alert state health departments when they diagnose farmworkers with the flu, using tests that detect influenza viruses, broadly. State health departments then confirm the test, and if it’s positive, they send a person’s sample to a CDC laboratory, where it is checked for the H5N1 virus, specifically. “Thus far we have received 23,” Shah said. “All but one of those was negative.”

State health departments are also monitoring around 150 people, he said, who have spent time around cattle. They’re checking in with these farmworkers via phone calls, text messages, or in-person visits to see if they develop symptoms. And if that happens, they’ll be tested.

Another way to assess farmworkers would be to check their blood for antibodies against the H5N1 bird flu virus; a positive result would indicate they might have been unknowingly infected. But Shah said health officials are not yet doing this.

“The fact that we’re four months in and haven’t done this isn’t a good sign,” Worobey said. “I’m not super worried about a pandemic at the moment, but we should start acting like we don’t want it to happen.”

Fact Check: Contrary to social-media posts, there is still no evidence that Covid-19 vaccines increase your risk of cancer

By Catalina Jaramillo
FactCheck.org

It has not been shown that Covid-19 vaccines cause or accelerate cancer. Yet opponents of the vaccines say a new review article “has found that Covid-19 mRNA vaccines could aid cancer development.” That statement is based mainly on misinterpretation of a study on mRNA cancer vaccines in mice.

Clinical trials, involving thousands of people, and multiple studies have shown that the mRNA Covid-19 vaccines from Pfizer/BioNTech and Moderna are safe. Hundreds of millions of doses have been administered under close monitoring systems that have found serious side effects are rare. Studies have also shown that the vaccines work very well in preventing severe Covid-19 disease and death, saving millions of lives across the globe.
 
There is no evidence to support a link between Covid-19 vaccines and cancer, as we’ve reported. Both the National Cancer Institute and the American Cancer Society have stated there’s no information that suggests COVID-19 vaccines cause cancer, make it more aggressive or lead to recurrence of cancer.

Yet, vaccine opponents falsely claim a review article published in April proves the contrary.

“A review in the International Journal of Biological Macromolecules has found that Covid-19 mRNA vaccines could aid cancer development,” reads an April 16 Facebook post by America’s Frontline Doctors, a group that has repeatedly spread misinformation about the pandemic -- and whose founder was sentenced to 60 days in prison for entering the U.S. Capitol during the Jan. 6 riot. Other posts made similar, baseless claims.

Messenger RNA, or mRNA, vaccines work by instructing a small number of a person’s cells to make specific proteins, which then prompt the body to mount an immune response. They use N1-methylpseudouridine, a modification naturally found in some RNA molecules, to allow the mRNA to deliver its message to the cell without being destroyed by an innate immune response.

The review paper being cited is based on other published articles and does not contain original research. Experts told us that it misleads by misinterpreting several studies and the role of N1-methylpseudouridine in vaccines. The authors also refer to an unreliable review article, written by authors known for spreading misinformation, that falsely claimed the mRNA Covid-19 vaccines impair the immune system and increase the risk of cancer, as we have explained.

One of the most important misrepresentations, and one that the authors heavily rely on, is based on the findings of a study on mRNA cancer vaccines in mice. The study looked at the efficacy of mRNA cancer vaccines with different degrees of N1-methylpseudouridine modification in a mouse melanoma model. According to the review, the study found that “adding 100% of N1-methyl-pseudouridine (m1Ψ) to the mRNA vaccine in a melanoma model stimulated cancer growth and metastasis, while non-modified mRNA vaccines induced opposite results, thus suggesting that Covic-19 mRNA vaccines could aid cancer development.”

But that’s not what the study found.

“Our results did not show, suggest or indicate that modified mRNA promotes tumor growth/metastasis,” Tanapat Palaga, professor of microbiology at the Chulalongkorn University in Thailand and the corresponding author of that study, told us in an email.

What the study actually showed is that both unmodified mRNA and modified mRNA induced immune responses against the tumor antigens, but only the unmodified mRNA reduced cancer growth and metastasis, while the modified mRNA didn’t. The study was published in 2022 and co-authored by Drew Weissman, who won the 2023 Nobel Prize with Katalin KarikĂ³ for discovering this mRNA modification that eventually led to the mRNA Covid-19 vaccines.

Dr. James A. Hoxie, an emeritus professor of medicine at the University of Pennsylvania and co-director of the Penn Institute of RNA Innovation (directed by Weissman), told us those findings are relevant for scientists who are studying ways in which mRNA cancer vaccines can elicit immune responses needed to prevent or delay cancer progression. (See “Social Media Posts Misinterpret Biden on mRNA Cancer Vaccines” for more information about mRNA cancer vaccines.)

“But that is a far cry from saying that the vaccine that was used to prevent Covid-19 disease causes cancer,” he said. Implying that by regulating the innate immune system, which is something scientists working in immunotherapies are trying to understand, “you’re leaving yourself open for cancer risk — that is ludicrous.”

Palaga told us, “I believe that the authors of this review article intentionally or [unintentionally] misinterpret our results and tried to twist the conclusion to support their agenda.”

There are no studies supporting a link between N1-methylpseudouridine and cancer in animals or mice, experts told us.

There is also no evidence mRNA Covid-19 vaccines impair, much less suppress, the immune system, as we’ve reported. In fact, the vaccines enhance immunity by teaching the immune system how to identify and fight the coronavirus.

N1-methylpseudouridine and its role in mRNA vaccines

To understand the role of N1-methylpseudouridine we have to look back at the history of mRNA vaccines.

Normally, when a cell encounters a foreign RNA, a molecule present in most living organisms and viruses, it activates a strong innate immune response against the molecule.

This was a problem for scientists trying to use mRNA as a therapeutic, since the goal was for the cell to receive the instructions carried by the mRNA and produce certain proteins. Until the mid-2000s, KarikĂ³, Weissman and others observed that if they attached certain chemical modifications found in some kinds of natural RNA molecules, such as pseudouridine, into one of the four bases of mRNA, they could blunt that innate immune response and, at the same time, increase the mRNA’s capacity to translate its code for the cell to make the desired proteins.

Later, scientists found N1-methylpseudouridine, another modification naturally found in some kinds of RNA molecules, worked better than pseudouridine.

The modification is not “suppressing” the immune system, Hoxie told us — it just allows for certain parts of the immune system not to activate temporarily “in order to get the desired effect.”

Jordan L. Meier, senior investigator at the National Cancer Institute who has studied the role of N1-methylpseudouridine in Covid-19 vaccines, told us the authors of the review paper misrepresent what N1-methylpseudouridine, which is abbreviated as m1Ψ, does.

The review “incorrectly” confuses “m1Ψ’s ability to hide from the immune system with an ability to weaken or disable it,” he told us in an email.

To explain it, Meier compared the mRNA modification to a spy using a disguise in order to pass security guards.

“The authors are essentially suggesting that the disguise somehow makes the guards less able to do their jobs going forward,” he wrote. “In reality, once the disguised person is through, the guards remain just as vigilant and capable as before.”

The review, he added, doesn’t provide evidence that N1-methylpseudouridine “leaves the immune system any worse off for future threats.”
 
Misrepresented studies in the review paper

Similarly, the review misleads by cherry-picking or misrepresenting figures and tables of this and other papers.

For example, in the study by Palaga, Weissman and others using a mouse melanoma model (in which malignant cells from a tumor are given to a mouse), scientists found that relative to mice that received no vaccine (and instead received a saline solution) no increase in tumor growth or decrease in survival occurred when animals were vaccinated with a modified mRNA vaccine.

However, when animals received a vaccine containing unmodified mRNA, the study showed a decrease in tumor growth and an increase in survival compared with the control group that received the saline solution. In other words, the study found that the unmodified mRNA generated immune responses that decreased tumor growth and improved survival, while, similar to the control group, the modified mRNA had no effect on the tumor.

Table 1 of the review, however, incorrectly says the study found that the modified mRNA vaccine “increases tumor growth” and “decreases survival.”

Hoxie said, “This is simply not true and is a gross misrepresentation of the data that paper actually shows. The modified RNA had no effect on the tumor, and results using that vaccine were the same as using a saline solution.”

The tumor growth in mice receiving the modified mRNA was “increased relative to the unmodified vaccine, but it was identical to when there was no intervention,” Hoxie said. “Animals that received the modified mRNA vaccine died at the same rate and with the same amount of tumor as did animals that received the saline solution. The fact tumor progression in this model was reduced with the unmodified mRNA vaccine is the key point of this paper and indicated that in this model immune responses to unmodified mRNA may have anti-tumor activity, an important finding for the cancer immunotherapy field.”

The review also refers to a study that has been extensively misinterpreted to falsely claim that the Pfizer/BioNTech mRNA Covid-19 vaccine causes what vaccine opponents called “turbo cancer.” The study describes one mouse that died from a lymphoma after 14 mice were given a high dose of the vaccine. The review paper reproduces images from the study that show dissected mice and compares the organs of the mouse that died with one with a normal anatomy.

As we explained, and as the authors of that paper noted in an addendum, there is no such thing as “turbo cancer,” and, more importantly, the case report does not demonstrate a causal relationship between the lymphoma and the vaccine.

Meier told us the review also wrongly refers to a study published in 2016 to support its thesis that modified mRNA vaccines turn off an immune sensor known as RIG-I.

“In reality, this study only showed m1Y mRNAs are unable to activate RIG-I and did not test inhibition. In other words, what was shown was that m1Y is a strong camouflage, not that it is an immune suppressor,” he wrote.

FactCheck.org is a nonpartisan, nonprofit organization at the University of Pennsylvania that monitors the factual accuracy of public statements.